RGD peptide (GRGDNP) (TFA)作为整合素-配体相互作用的抑制剂,在细胞黏附、迁移、生长和分化中发挥重要作用。RGD peptide (GRGDNP) (TFA)通过激活构象变化促进细胞凋亡,从而增强caspase-3的活化。
编号:182326
CAS号:114681-65-1/120103-89-1
单字母:H2N-GRGDNP-OH
RGD peptide (GRGDNP) 作为整合素-配体相互作用的抑制剂,在细胞黏附、迁移、生长和分化中发挥重要作用。RGD peptide (GRGDNP) 通过激活构象变化促进细胞凋亡,从而增强caspase-3的活化。
RGD peptide (GRGDNP) acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation[1]. RGD peptide (GRGDNP) promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing[2][3].
DOI | 名称 | |
---|---|---|
10.1006/excr.1996.0243 | Common Principles in Cell Adhesion | 下载 |
10.1074/jbc.274.13.8524 | Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1 | 下载 |
10.1016/S0962-8924(97)01002-7 | Integrins, adhesion and apoptosis | 下载 |