988-75-0,二肽Z-Glu-Tyr,Cbz-Glu-Tyr-COOH,Z-EY-OH,安徽专肽生物的产品

二肽Z-Glu-Tyr
猪组织蛋白酶 A 和酸性羧肽酶的底物。

编号：200423

CAS号：988-75-0

单字母：Z-EY-OH

编号:	200423
中文名称:	二肽Z-Glu-Tyr
CAS号:	988-75-0
单字母:	Z-EY-OH
三字母:	Cbz N端Cbz保护，苄氧羰基（Cbz，Z） -Glu L-谷氨酸：glutamic acid。系统命名为(2S)-氨基-戊二酸。是编码氨基酸。符号：E，Glu。D-谷氨酸存在于多种细菌的细胞壁和某些细菌杆菌肽中。 -Tyr L-酪氨酸：tyrosine。系统命名为(2S)-氨基-3-(4-羟基苯基)丙酸。是编码氨基酸。符号：Y，Tyr。 -OH C端羧基：C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时，通常将C端放在肽链的右边。
氨基酸个数:	2
分子式:	C₂₂H₂₄O₈N₂
平均分子量:	444.43
精确分子量:	444.15
等电点(PI):	7.11
pH=7.0时的净电荷数:	-
平均亲水性:	-0.2
疏水性值:	-2.2
消光系数:	1490
来源:	人工化学合成，仅限科学研究使用，不得用于人体。
储存条件:	负80℃至负20℃
标签:	CBZ修饰肽 600+种二肽(Dipeptide)现货

Substrate for porcine cathepsin A and acid carboxypeptidases from A. niger.and A. kawachii.

Z-Glu-Tyr is a synthetic substrate of the enzyme cathepsin B. The amino acid sequence of Z-Glu-Tyr has been shown to be identical to the sequence of the natural substrate, L-glutaminyl-L-tyrosine. The activity of the enzyme cathepsin B can be inhibited by Z-Glu-Tyr due to its ability to form a covalent bond with cysteine residues in the active site. This inhibition prevents cleavage of peptide bonds and synthesis of polypeptides, which are necessary for cell growth and division. Z-Glu-Tyr is also an inhibitor of thiol proteases, such as papain and subtilisin, which are enzymes that hydrolyze peptide bonds in proteins.

DOI	名称
10.1093/oxfordjournals.jbchem.a130461	Stabilization of pig kidney cathepsin A by sucrose and chloride ion, and inhibition of the enzyme activity by diisopropyl fluorophosphate and sulfhydryl reagents	下载
10.1016/0005-2744(81)90060-7	Enzymatic properties of an acid carboxypeptidase from Aspergillus niger var. macrosporus	下载
10.1271/bbb.57.618	Purification and characterization of serine carboxypeptidases from Absidia zychae	下载
10.1093/oxfordjournals.jbchem.a021994	Bovine spleen cathepsin A: characterization and comparison with the protective protein	下载